Friday, June 3, 2016

Administration of Vasoconstrictor, But Not Volume Expander Prevents Maternal Hypotension During Spinal-Epidural Anesthesia For Elective Cesarean Section

Administration of vasoconstrictor preventing maternal hypotension after combined spinal-epidural , anesthesia(CSEA) in elective cesarean section patients.A total of 240 full-term, single pregnancy women, undergoing elective cesarean section in CSEA were included. Multiple linear regression analysis was used to identify major contributing factors for maternal hypotension from 18 independent variables. The model was set as ╬▒entry= 0.05, ╬▒remove = 0.15, and condition index <15. The incidence of hypotension from different combinations of vasoconstrictors for hypotension prevention were calculated and compared, then correlated with pH and base excess in neonatal umbilical venous blood, as well as 1 and 5 min Apgar score, using one-way ANOVA. p<0.05 was considered to be significant difference. Continuous dosage of phenylephrine decrease incidence of maternal hypotension after CSEA for elected cesarean section.

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