The general idea that emerged from the experiments, made in our laboratoires, was that Echinodermata, as exemplified by sea stars: Asterina gibbosa and Asterias Rubens, possessed an immune system, with B cell lymphocytes, able to mount cellular and humoral-specific responses, after stimulation with a foreign antigen [1]. Asterias Rubens produced ‘‘An antibody’’ anti HRP after injections to HRP, it was shown to correlate to kappa genes, in 2011 [2]. In 2013-2014 a sea star
Ig Kappa gene to HRP was cloned [3,4]. This gene of which, here is the sequence
Ig Kappa gene to HRP was cloned [3,4]. This gene of which, here is the sequence
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